The Senior Director / Executive Director, Global Supply Chain & Logistics will support corporate objectives by providing end-to-end strategic leadership and execution across global clinical and commercial supply operations. This role is responsible for ensuring uninterrupted, compliant, and cost-effective supply of drug product from early clinical development through commercialization.
This position serves as a key cross-functional leader, partnering closely with Clinical Operations, CMC, Regulatory Affairs, Quality, Finance, and external partners to manage complex global supply networks in a dynamic and collaborative environment. The role oversees supply strategy, demand planning, external packaging and labeling, global logistics, budgets, risk management, and readiness for clinical studies and commercial launch.
Key Responsibilities
- Develop and lead integrated global supply chain strategies supporting Phase 1–3 clinical trials and commercial readiness.
- Design scalable supply models aligned with development timelines, portfolio priorities, and anticipated commercial demand.
- Ensure uninterrupted supply of drug product and packaged clinical and commercial materials.
- Lead and manage global packaging, labeling, and depot networks, ensuring capacity, capability, and performance.
- Lead global demand forecasting and supply planning activities, including scenario modeling and risk mitigation.
- Align supply plans with Finance, Manufacturing, and Program teams to support budgets and production planning.
- Oversee global logistics, cold-chain distribution, packaging, and labeling strategies in compliance with global regulations.
- Support NDA and MAA submissions by providing supply, manufacturing, and logistics inputs.
- Lead launch readiness planning, including inventory strategy, commercial handoff, and clinical-to-commercial transitions.
- Ensure GxP and GDP compliance across internal operations and external partners; support audits and inspections.
- Own supply chain budgets, cost control, and financial forecasting.
- Build and lead high-performing global supply chain teams and establish a culture of operational excellence.
- Proactively identify, assess, and mitigate supply risks across development and commercial stages.
- Communicate complex supply chain topics clearly to cross-functional teams and senior leadership.
Qualifications & Experience
- Bachelor’s degree in Engineering, Supply Chain, Pharmacy, Life Sciences, or a related field; advanced degree preferred.
- 15+ years of progressive experience in pharmaceutical or biotechnology supply chain roles.
- Significant experience managing global external supply chain/depot networks.
- Demonstrated experience supporting NDA/MAA submissions and commercial product launches.
- Deep understanding of the drug development lifecycle from IND through commercialization.
- Proven ability to lead cross-functional, global teams and influence at senior leadership levels.
- Strong risk management, problem-solving, and decision-making skills in complex environments.
- Excellent organizational, communication, and interpersonal skills.
- Ability to thrive in a fast-paced environment with ambiguity and competing priorities.
- Authorization to work in the United States.
- Ability to travel up to approximately 15%
Pay Range and Benefits
Base Salary Range: $255,513 - $270,040 USD
Individual compensation will be determined based on factors such as work location, skills, education, training, and experience.
What we offer US-based Employees:
- Competitive base, bonus, new hire and ongoing equity packages
- The starting compensation range(s) for this role is for a full-time employee (FTE) basis
- Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment
- Employer-paid Medical, dental, and vision insurance
- Employer-paid life insurance, AD&D, short-term disability, long-term disability, and EAP coverage
- 401(k) Plan with a fully vested company match 1:1 up to 4% of contributions
- Employee Stock Purchase Plan
- 14 -18 paid holidays, including office closure between December 25th and January 1st
- Flexible vacation
- Sick time
- Fitness Program
- Get Outdoors Program
- Paid parental leave benefit
- Tuition assistance
Job Type: Full-Time
Work authorization: United States (Required)
Work Location: Remote
Equal Opportunity Employer: Tyra Biosciences, Inc. is an equal opportunity employer that is committed to providing a work environment free of harassment and discrimination based upon a protected category, as well as an environment free from retaliation for protected activity.
Notice to Recruiters and Third-Party Agencies: The Talent Acquisition team manages the recruitment and employment process for Tyra. To protect the interests of all parties involved, Tyra will only accept resumes from a recruiter once a fully executed search agreement is in place. Agencies are hereby specifically directed not to contact Tyra employees directly in an attempt to present candidates. Tyra will consider any candidate for whom an Agency and/or Recruiter has submitted an unsolicited resume to have been referred, free of any charges or fees.
